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Symptoms and Signs – Differential Diagnosis of Migraine
Chronic/persistent
In the presence of other cognitive deficits
Infection: herpes simplex encephalitis
Inflammation: limbic encephalitis (may be paraneoplastic), sarcoidosis
Medial temporal lobe lesions (bilateral)
Toxic metabolic: thiamine deficiency (Korsakoff's psychosis in alcoholism, hyperemesis gravidarum)
Transient ischaemic attack (TIA), tumours (rare)
Tumours: midline (in the region of the third ventricle)
Vascular: posterior cerebral artery occlusion (bilateral)
Chronic/persistent
In the presence of other cognitive deficits
Infection: herpes simplex encephalitis
Inflammation: limbic encephalitis (may be paraneoplastic), sarcoidosis
Medial temporal lobe lesions (bilateral)
Toxic metabolic: thiamine deficiency (Korsakoff's psychosis in alcoholism, hyperemesis gravidarum)
Transient ischaemic attack (TIA), tumours (rare)
Tumours: midline (in the region of the third ventricle)
Vascular: posterior cerebral artery occlusion (bilateral)
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