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​Symptoms and Signs – Differential Diagnosis of Molluscum Contagiosum
• Basal cell carcinoma: multiple lesions are absent
• Cutaneous cryptococcosis in AIDS patients: budding yeasts will be present on cytologic examination of the lesions
• Folliculitis: no central umbilication, presence of hair piercing the pustule or papule
• Herpes simplex: lesions become rapidly umbilicated
• Varicella: blisters and vesicles are present
• Verruca plana (flat warts): no central umbilication, not dome shaped, irregular surface, can involve palms and soles
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