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Symptoms and Signs – Differential Diagnosis of Myalgia
Acute angle closure glaucoma
Acute metabolic encephalopathy
Alzheimer's disease
Chronic fatigue syndrome
Congenital
Creutzfeldt-Jakob disease
Deep coma, cerebral death
Drugs: mydriatic eye drops (antimuscarinics, e.g. atropine, cyclopentolate, tropicamide), overdose (cocaine, amphetamine, glutethamide), poisoning, e.g. belladonna
Fibromyalgia
Holmes-Adie pupil (degeneration of the nerve to the ciliary ganglion)
Infection: systemic
Inflammatory/connective tissue disease
Lysosomal storage diseases, e.g. Gaucher's disease, Tay-Sachs disease
Malignancy
Malignant hyperpyrexia
Muscle haematoma, abscess
Mydriasis
Myoclonus
Myopathy: metabolic, inflammatory, infective, drugs,
Parkinson's disease
Polymyalgia rheumatica
Third nerve palsy
Trauma: post-traumatic iridoplegia, iridectomy, lens implant


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