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Symptoms and Signs – Differential Diagnosis of Neck Swelling
Midline
Hard: bony tumour or plasmacytoma
Lymph nodes
Manubrium swelling:
Pulsatile: eroding aortic aneurysm
Rare: sublingual dermoid cyst, pharyngeal pouch, plunging ranula, subhyoid bursa, laryngeal/tracheal/oesophageal carcinoma
Soft: lipoma
Thyroglossal cyst
Thyroid gland swelling

Anterior triangle

Branchial cyst
Carotid body aneurysm
Carotid body tumour
Lymph nodes, cold abscess (TB)
Salivary gland {submandibular/parotid) swelling
Sternomastoid tumour

Posterior triangle
Cystic hygroma
Lymph nodes, cold abscess {TB)
Subclavian artery aneurysm
Tumour of clavicle


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