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Symptoms and Signs – Differential Diagnosis of Paraplegia
• Trauma: penetrating wounds to motor cortex, fracture-dislocation of vertebral column with compression of spinal cord or cauda equina, prolapsed disk, electrical injuries
• Thrombosis of superior sagittal sinus
• Polyneuritis: Guillain-Barré syndrome, diabetes, alcohol, beriberi,
• Neoplasm: parasagittal region, vertebrae, meninges, spinal cord, cauda equina; Hodgkin’s disease, non-Hodgkin’s lymphoma (NHL), leukemic deposits, pelvic neoplasms
• Multiple sclerosis (MS) and other demyelinating disorders
• Mechanical compression of spinal cord, cauda equina, or lumbosacral plexus: Paget’s disease, kyphoscoliosis, herniation of intervertebral disk, spondylosis, ankylosing spondylitis, rheumatoid arthritis (RA), aortic aneurysm
• Infections: spinal abscess, syphilis, TB, poliomyelitis, leprosy
• Heredofamilial muscular dystrophies
• Amyotrophic lateral sclerosis (ALS)
• Congenital and familial conditions: syringomyelia, myelomeningocele, myelodysplasia
• Hysteria and heavy metals.
• Trauma: penetrating wounds to motor cortex, fracture-dislocation of vertebral column with compression of spinal cord or cauda equina, prolapsed disk, electrical injuries
• Thrombosis of superior sagittal sinus
• Polyneuritis: Guillain-Barré syndrome, diabetes, alcohol, beriberi,
• Neoplasm: parasagittal region, vertebrae, meninges, spinal cord, cauda equina; Hodgkin’s disease, non-Hodgkin’s lymphoma (NHL), leukemic deposits, pelvic neoplasms
• Multiple sclerosis (MS) and other demyelinating disorders
• Mechanical compression of spinal cord, cauda equina, or lumbosacral plexus: Paget’s disease, kyphoscoliosis, herniation of intervertebral disk, spondylosis, ankylosing spondylitis, rheumatoid arthritis (RA), aortic aneurysm
• Infections: spinal abscess, syphilis, TB, poliomyelitis, leprosy
• Heredofamilial muscular dystrophies
• Amyotrophic lateral sclerosis (ALS)
• Congenital and familial conditions: syringomyelia, myelomeningocele, myelodysplasia
• Hysteria and heavy metals.
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