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MEDICINE 

Symptoms and Signs -Differential Diagnosis of Paroxysmal Nocturnal Dyspnea

11/29/2024

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Symptoms and Signs -Differential Diagnosis of Paroxysmal Nocturnal Dyspnea
This indication, often dramatic and frightening for the patient, indicates an episode of dyspnea that suddenly rouses the individual from sleep. Typical observations encompass diaphoresis, coughing, wheezing, and chest discomfort. The episode diminishes if the patient sits up or stands for several minutes, but may reoccur every 2 to 3 hours.

Paroxysmal nocturnal dyspnea indicates left-sided heart failure. This may arise from diminished respiratory drive, compromised left ventricular function, augmented reabsorption of interstitial fluid, or elevated thoracic blood volume. All of these pathophysiological pathways exacerbate dyspnea when the patient assumes a supine position.

Medical History and Physical Assessment
Commence by investigating the patient's report of dyspnea. Does he experience dyspneic bouts exclusively at night, or do they occur at other times, such as post-exertion or while seated? What specific action provokes the attack? Does he exhibit coughing, wheezing, weariness, or weakness during an episode? Determine whether he has a history of lower extremity edema or jugular vein distention.

Inquire whether he sleeps with his head up, and if so, the number of pillows used, or if he sleeps in a reclined chair. Acquire a cardiopulmonary medical history. Does the patient or a family member have a history of myocardial infarction, coronary artery disease, hypertension, chronic bronchitis, emphysema, or asthma? Has the patient undergone cardiac surgery? Subsequently, conduct a physical examination. Commence by assessing the patient's vital signs and developing a comprehensive image of his look. Is he visibly cyanotic or edematous? Examine the lungs for crackles and wheezing, and assess the heart for gallops and arrhythmias.

Etiological Factors
Left ventricular heart failure
Dyspnea—during activity, when sleeping, and ultimately at rest—is an initial indicator of left-sided heart failure. This symptom is typically associated with Cheyne-Stokes respirations, diaphoresis, weakness, wheezing, and a chronic nonproductive cough or a cough that yields clear or blood-tinged sputum. As the patient's condition deteriorates, he exhibits tachycardia, tachypnea, an alternating pulse (often triggered by a premature beat), a ventricular gallop, crackles, and peripheral edema.

In late left-sided heart failure, the patient may present with pronounced orthopnea, cyanosis, clubbing, hemoptysis, and cardiac arrhythmias, alongside manifestations of shock, including hypotension, a weak pulse, and cold, clammy skin.

Prepare the patient for diagnostic evaluations, including a chest X-ray, echocardiography, exercise electrocardiography, and cardiac blood pool imaging. Should the hospitalized patient exhibit paroxysmal nocturnal dyspnea, assist him into a sitting position or facilitate ambulation within the room.

Administer supplementary oxygen if required. Attempt to soothe him, as anxiety may intensify dyspnea. Elucidate the signs and symptoms necessitating urgent medical intervention, and examine nutritional and fluid limitations. Investigate postures that may facilitate respiration, and provide instruction on required pharmacological treatments. In a child, paroxysmal nocturnal dyspnea typically arises from a congenital cardiac abnormality that leads to heart failure. Alleviate the child's dyspnea by raising his head and soothing him.


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