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Symptoms and Signs – Differential Diagnosis of Proximal muscle weakness
Toxic/metabolic: steroids, Cushing's syndrome, thyrotoxicosis, hypothyroidism, osteomalacia
Inflammatory: dermatomyositis, polymyositis, polymyalgia rheumatica lnfecti_on: staphylococcal myositis, parasites (trichinosis, cysticercosis), viral
(influenza, coxsackie, echo)
Inherited: muscular dystrophies, metabolic myopathies (e.g. glycogen storage
diseases e.g. McArdle's syndrome), mitochondrial myopathies, familial periodic paralysis (associated with hypo/hyperkalaemia)
Toxic/metabolic: steroids, Cushing's syndrome, thyrotoxicosis, hypothyroidism, osteomalacia
Inflammatory: dermatomyositis, polymyositis, polymyalgia rheumatica lnfecti_on: staphylococcal myositis, parasites (trichinosis, cysticercosis), viral
(influenza, coxsackie, echo)
Inherited: muscular dystrophies, metabolic myopathies (e.g. glycogen storage
diseases e.g. McArdle's syndrome), mitochondrial myopathies, familial periodic paralysis (associated with hypo/hyperkalaemia)
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