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Symptoms and Signs – Differential Diagnosis of Restless Legs Syndrome
• Anxiety and mood disorders
• Chronic fatigue
• Chronic renal failure
• Dyskinesias while awake
• Hemolytic anemia (sickle cell crisis, thalassemia major, autoimmune hemolysis)
• Hemorrhage
• Neuroleptic-induced akathisia
• Nocturnal leg cramps with or without peripheral artery disease Reticulocytosis
• Other sleep disorders
• Periodic limb movement disorder (PLMD), repetitive limb movements (lower extremities or upper extremities) occurring during sleep; associated with arousals from sleep and daytime sleeping; patient is typically unaware, but bed partner reports restlessness or kicking during sleep
• Peripheral neuropathy and radiculopathy
• Post anemia therapy (folic acid, ferrous sulfate, vitamin B12)
• Anxiety and mood disorders
• Chronic fatigue
• Chronic renal failure
• Dyskinesias while awake
• Hemolytic anemia (sickle cell crisis, thalassemia major, autoimmune hemolysis)
• Hemorrhage
• Neuroleptic-induced akathisia
• Nocturnal leg cramps with or without peripheral artery disease Reticulocytosis
• Other sleep disorders
• Periodic limb movement disorder (PLMD), repetitive limb movements (lower extremities or upper extremities) occurring during sleep; associated with arousals from sleep and daytime sleeping; patient is typically unaware, but bed partner reports restlessness or kicking during sleep
• Peripheral neuropathy and radiculopathy
• Post anemia therapy (folic acid, ferrous sulfate, vitamin B12)
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