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Symptoms and Signs – Differential Diagnosis of Schizophrenia
• Any medical condition, medicine, or substance of abuse that can affect brain homeostasis and cause psychosis: distinguished from schizophrenia by its relatively brief course and the alteration in mental status that could suggest an underlying delirium
• Autism in the adult: has an early age at onset and lacks significant hallucinations or delusions
• Delusional disorder: has nonbizarre delusions and lacks the thought disturbance, hallucinations, and negative symptoms of schizophrenia
• Mood disorders with psychosis: indistinguishable from schizophrenia cross-sectionally but have a longitudinal course that includes full recovery
• Other neurologic conditions (e.g., Huntington’s) that have psychosis as the initial presentation
• Other psychiatric disorders: source of greatest confusion
• Any medical condition, medicine, or substance of abuse that can affect brain homeostasis and cause psychosis: distinguished from schizophrenia by its relatively brief course and the alteration in mental status that could suggest an underlying delirium
• Autism in the adult: has an early age at onset and lacks significant hallucinations or delusions
• Delusional disorder: has nonbizarre delusions and lacks the thought disturbance, hallucinations, and negative symptoms of schizophrenia
• Mood disorders with psychosis: indistinguishable from schizophrenia cross-sectionally but have a longitudinal course that includes full recovery
• Other neurologic conditions (e.g., Huntington’s) that have psychosis as the initial presentation
• Other psychiatric disorders: source of greatest confusion
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