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Symptoms and Signs – Differential Diagnosis of Spastic paraparesis
Cord compression (cervical spondylosis, disc prolapse, secondary tumour in spine, spinal cord tumour)
Multiple sclerosis
Motor neurone disease
Trauma, birth injury (cerebral palsy) Syringomyelia
Others
Vascular: anterior spinal artery thrombosis, venous sinus thrombosis, multiple cerebral infarctions
Infection: tranverse myelitis (post-infectious, e.g. Mycoplasma), HIV, HTLV-1 (tropical spastic paraparesis), syphilis
Tumours: parasigittal meningioma
Toxic/metabolic: 812 deficiency (subacute combined degeneration)
Congenital: hereditary spastic paraparesis, Friedreich's ataxia
Cord compression (cervical spondylosis, disc prolapse, secondary tumour in spine, spinal cord tumour)
Multiple sclerosis
Motor neurone disease
Trauma, birth injury (cerebral palsy) Syringomyelia
Others
Vascular: anterior spinal artery thrombosis, venous sinus thrombosis, multiple cerebral infarctions
Infection: tranverse myelitis (post-infectious, e.g. Mycoplasma), HIV, HTLV-1 (tropical spastic paraparesis), syphilis
Tumours: parasigittal meningioma
Toxic/metabolic: 812 deficiency (subacute combined degeneration)
Congenital: hereditary spastic paraparesis, Friedreich's ataxia
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