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Symptoms and Signs – Differential Diagnosis of Stomatitis, White Lesions
• Brain and CNS dysfunction
• Candidiasis (thrush)
• Chemical injury: white sloughing mucosa
• CNS tumors
• Darier’s disease (keratosis follicularis): white papules on the gingivae, alveolar mucosa, and dorsal tongue; skin lesions also present (erythematous papules); inherited as an autosomal dominant trait
• Discoid lupus erythematosus: lesion resembles lichen planus
• Hairy leukoplakia: shaggy white surface that cannot be wiped off; seen in HIV infection, caused by Epstein-Barr virus (EBV) Strabismus
• Leukoedema: filmy opalescent-appearing mucosa, which can be reverted to normal appearance by stretching. This condition is benign.
• Leukoplakia: white lesions that cannot be scraped off; 20% are premalignant epithelial dysplasia or squamous cell carcinoma
• Lichen planus: linear, reticular, slightly raised striae on buccal mucosa; skin is involved by pruritic violaceous papules on forearms and inner thighs
• Nicotine stomatitis: whitened palate with red papules
• Orbital tumors
• Refractive errors
• White sponge nevus: thick, white corrugated folds involving the buccal mucosa; appears in childhood as an autosomal dominant trait; benign condition
• Brain and CNS dysfunction
• Candidiasis (thrush)
• Chemical injury: white sloughing mucosa
• CNS tumors
• Darier’s disease (keratosis follicularis): white papules on the gingivae, alveolar mucosa, and dorsal tongue; skin lesions also present (erythematous papules); inherited as an autosomal dominant trait
• Discoid lupus erythematosus: lesion resembles lichen planus
• Hairy leukoplakia: shaggy white surface that cannot be wiped off; seen in HIV infection, caused by Epstein-Barr virus (EBV) Strabismus
• Leukoedema: filmy opalescent-appearing mucosa, which can be reverted to normal appearance by stretching. This condition is benign.
• Leukoplakia: white lesions that cannot be scraped off; 20% are premalignant epithelial dysplasia or squamous cell carcinoma
• Lichen planus: linear, reticular, slightly raised striae on buccal mucosa; skin is involved by pruritic violaceous papules on forearms and inner thighs
• Nicotine stomatitis: whitened palate with red papules
• Orbital tumors
• Refractive errors
• White sponge nevus: thick, white corrugated folds involving the buccal mucosa; appears in childhood as an autosomal dominant trait; benign condition
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