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Symptoms and Signs – Differential Diagnosis of Testicular Size Variations
SMALL TESTES
• Normal variant
• Hypothalamic-pituitary dysfunction
• Gonadotropin deficiency
• Growth hormone deficiency
• Primary hypogonadism
• Autoimmune destruction, chemotherapy, cryptorchidism, irradiation, Klinefelter’s syndrome, orchiditis, testicular regression syndrome, torsion, trauma
LARGE TESTES
• Adrenal rest tissue
• Compensatory
• Fragile X syndrome
• Idiopathic
• Tumor
SMALL TESTES
• Normal variant
• Hypothalamic-pituitary dysfunction
• Gonadotropin deficiency
• Growth hormone deficiency
• Primary hypogonadism
• Autoimmune destruction, chemotherapy, cryptorchidism, irradiation, Klinefelter’s syndrome, orchiditis, testicular regression syndrome, torsion, trauma
LARGE TESTES
• Adrenal rest tissue
• Compensatory
• Fragile X syndrome
• Idiopathic
• Tumor
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