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Symptoms and Signs – Differential Diagnosis of Dry eyes
Corneal epitheliopathy: trigeminal dysfunction, contact lens use
Drugs: antihistamines, antidepressants, 13-blockers, contraceptive pills, diuretics
radiation), reduced Mucin layer (reduced vitamin A, burns, circatricial pemphigoid)
Reduced Eyelid closure: facial nerve palsy, Graves' disease, prolonged reading
Reduced Tear production: reduced Lipid layer (blepharitis), reduced Aqueous layer (involvement of lacrimal glands: Sjogren's syndrome, rheumatoid arthritis, SLE, surgery,


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Symptoms and Signs – Differential Diagnosis of Dysgeusia
Chronic nasal blockage
Old age
Facial nerve palsy
Drugs/toxins: metronidazole, ACE inhibitors, anti-thyroid drugs, Lithium,
clarythromicin, heavy metals (e.g. lead poisoning)
Dental procedures
Rare:
Malignancy, bone marrow transplantation, GI (GORD, irritable bowel disease,
cirrhosis)
Nutritional: Zn/8 12 deficiency
Haemodialysis
HIV
Hypothyroidism
Depression


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Symptoms and Signs – Differential Diagnosis of Dysgeusia
Chronic nasal blockage
Old age
Facial nerve palsy
Drugs/toxins: metronidazole, ACE inhibitors, anti-thyroid drugs, Lithium,
clarythromicin, heavy metals (e.g. lead poisoning)
Dental procedures
Rare:
Malignancy, bone marrow transplantation, GI (GORD, irritable bowel disease,
cirrhosis)
Nutritional: Zn/8 12 deficiency
Haemodialysis
HIV
Hypothyroidism
Depression


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Symptoms and Signs – Differential Diagnosis of Ear ache
External ear
Boil, furuncle
Inclusion dermoid
Malignancy (e.g. squamous cell carcinoma, basal cell carcinoma)
Otitis externa
Trauma/subperichondral haematoma

Middle ear
Foreign body
Mastoiditis
Otitis media
Referred
Teeth
Temporomandibular joint
Tongue (tumour of the posterior third)
Tonsillitis, pharyngitis

Neurological
Herpes zoster
Glossopharyngeal neuralgia
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Symptoms and Signs – Differential Diagnosis of Dysuria
Prostatitis
Urethritis: chlamydia!, gonococcal, others: Trichomonas vagina/is, Candida albicans
Urinary tract infection: cystitis, urethritis, acute pyelonephritis (uncommon cause of dysuria)
Vaginitis: Candida albicans, Trichomonas vagina/is, bacterial vaginosis
Interstitial cystitis
Female urethral syndrome
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​Symptoms and Signs – Differential Diagnosis of Dyspareunia
Superficial
Psychological
syndrome, scleroderma), childbirth, episiotomy, surgery
Vagina: infection, atrophic vaginitis (post-menopausal), dryness (Sjogren's
Vulva: infection, dermatological disease, dysplasias

Deep
Endometriosis
Pelvic infection (chronic)
Pelvic mass
Irritable bowel syndrome
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