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Symptoms and Signs – Differential Diagnosis of Pilar Cyst (Wen)
• Sebaceous cyst
• Pilomatricoma
• Lipoma
• Epidermoid cyst
• Dermoid cyst
• Sebaceous cyst
• Pilomatricoma
• Lipoma
• Epidermoid cyst
• Dermoid cyst
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Symptoms and Signs – Differential Diagnosis of Pilonidal Disease
• Perianal abscess arising from the posterior midline crypt
• Osteomyelitis
• Hidradenitis suppurativa
• Furuncle
• Coccygeal sinus
• Carbuncle
• Anal fistula
• Perianal abscess arising from the posterior midline crypt
• Osteomyelitis
• Hidradenitis suppurativa
• Furuncle
• Coccygeal sinus
• Carbuncle
• Anal fistula
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Symptoms and Signs – Differential Diagnosis of Pinworms
• Perineal yeast/fungal infections
• Perianal itching related to poor hygiene
• Hemorrhoidal disease and anal fissures
• Perineal yeast/fungal infections
• Perianal itching related to poor hygiene
• Hemorrhoidal disease and anal fissures
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Symptoms and Signs – Differential Diagnosis of Pituitary Adenoma
PROLACTINOMA
• Pregnancy
• Postpartum puerperium
• Primary hypothyroidism
• Breast disease
• Breast stimulation
• Drug ingestion (especially phenothiazines, antidepressants, haloperidol, methyldopa, reserpine, opiates, amphetamines, and cimetidine)
• Chronic renal failure
• Liver disease
• Polycystic ovary disease
• Chest wall disorders
• Spinal cord lesions
• Previous cranial irradiation
ACROMEGALY
• Ectopic production of GH-releasing hormone from a carcinoid or other neuroendocrine tumor
CUSHING’S DISEASE
• Diseases that cause ectopic sources of ACTH overproduction (including small cell carcinoma of the lung, bronchial carcinoid, intestinal carcinoid, pancreatic islet cell tumor, medullary thyroid carcinoma, and pheochromocytoma)
• Adrenal adenomas, adrenal carcinoma
• Nelson’s syndrome
THYROTROPIN-SECRETING PITUITARY ADENOMAS
• Primary hypothyroidism
NONSECRETORY PITUITARY ADENOMA
• Non-neoplastic mass lesions of various etiologies (e.g., infectious, granulomatous)
PROLACTINOMA
• Pregnancy
• Postpartum puerperium
• Primary hypothyroidism
• Breast disease
• Breast stimulation
• Drug ingestion (especially phenothiazines, antidepressants, haloperidol, methyldopa, reserpine, opiates, amphetamines, and cimetidine)
• Chronic renal failure
• Liver disease
• Polycystic ovary disease
• Chest wall disorders
• Spinal cord lesions
• Previous cranial irradiation
ACROMEGALY
• Ectopic production of GH-releasing hormone from a carcinoid or other neuroendocrine tumor
CUSHING’S DISEASE
• Diseases that cause ectopic sources of ACTH overproduction (including small cell carcinoma of the lung, bronchial carcinoid, intestinal carcinoid, pancreatic islet cell tumor, medullary thyroid carcinoma, and pheochromocytoma)
• Adrenal adenomas, adrenal carcinoma
• Nelson’s syndrome
THYROTROPIN-SECRETING PITUITARY ADENOMAS
• Primary hypothyroidism
NONSECRETORY PITUITARY ADENOMA
• Non-neoplastic mass lesions of various etiologies (e.g., infectious, granulomatous)
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Symptoms and Signs – Differential Diagnosis of Pityriasis Alba
• Vitiligo
• Tinea
• Psoriasis
• Eczema
• Chemical leukoderma
• Vitiligo
• Tinea
• Psoriasis
• Eczema
• Chemical leukoderma
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Symptoms and Signs – Differential Diagnosis of Pityriasis Rosea
• Viral exanthem
• Tinea versicolor (the lesions are more brown and the borders are not as ovoid)
• Tinea corporis (can be ruled out by potassium hydroxide examination)
• Secondary syphilis (absence of herald patch, positive serologic test result for syphilis)
• Psoriasis
• Nummular eczema
• Lichen planus
• Eczema
• Drug eruption
• Viral exanthem
• Tinea versicolor (the lesions are more brown and the borders are not as ovoid)
• Tinea corporis (can be ruled out by potassium hydroxide examination)
• Secondary syphilis (absence of herald patch, positive serologic test result for syphilis)
• Psoriasis
• Nummular eczema
• Lichen planus
• Eczema
• Drug eruption
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Symptoms and Signs – Differential Diagnosis of Placenta Previa
• Vasa previa
• Vaginal or cervical trauma
• Placenta percreta
• Placenta increta
• Placenta accreta
• Local malignant neoplasm
• Labor
• Abruptio placentae
• Vasa previa
• Vaginal or cervical trauma
• Placenta percreta
• Placenta increta
• Placenta accreta
• Local malignant neoplasm
• Labor
• Abruptio placentae
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Symptoms and Signs – Differential Diagnosis of Plantar Fasciitis
• Tumor, infection
• Tarsal tunnel syndrome
• Stress fracture
• Other regional tendinitis
• Tumor, infection
• Tarsal tunnel syndrome
• Stress fracture
• Other regional tendinitis
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Symptoms and Signs – Differential Diagnosis of Peritoneal Effusion
TRANSUDATES
Increased Hydrostatic Pressure or Decreased Plasma
Oncotic Pressure
• Congestive heart failure (CHF)
• Hepatic cirrhosis
• Hypoproteinemia
EXUDATES
Increased Capillary Permeability or Decreased
Lymphatic Resorption
• Infections (TB, spontaneous bacterial peritonitis, secondary
bacterial peritonitis)
• Neoplasms (hepatoma, metastatic carcinoma, lymphoma,
mesothelioma)
• Trauma
• Pancreatitis
• Bile peritonitis (e.g., ruptured gallbladder)
CHYLOUS EFFUSION
Damage or Obstruction to Thoracic Duct
• Trauma
• Lymphoma
• Carcinoma
• Tuberculosis
• Parasitic infection
TRANSUDATES
Increased Hydrostatic Pressure or Decreased Plasma
Oncotic Pressure
• Congestive heart failure (CHF)
• Hepatic cirrhosis
• Hypoproteinemia
EXUDATES
Increased Capillary Permeability or Decreased
Lymphatic Resorption
• Infections (TB, spontaneous bacterial peritonitis, secondary
bacterial peritonitis)
• Neoplasms (hepatoma, metastatic carcinoma, lymphoma,
mesothelioma)
• Trauma
• Pancreatitis
• Bile peritonitis (e.g., ruptured gallbladder)
CHYLOUS EFFUSION
Damage or Obstruction to Thoracic Duct
• Trauma
• Lymphoma
• Carcinoma
• Tuberculosis
• Parasitic infection
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Symptoms and Signs – Differential Diagnosis of Secondary Peritonitis
• Urologic: nephrolithiasis, interstitial cystitis
• Spontaneous bacterial peritonitis
• Postoperative: abscess, sepsis, bowel obstruction, injury to internal organs
• Miscellaneous: abdominal trauma, penetrating wounds, infections secondary to intraperitoneal dialysis
• Gynecologic: ruptured ectopic pregnancy, pelvic inflammatory disease (PID), ruptured hemorrhagic ovarian cyst, ovarian torsion, degenerating leiomyoma
• Gastrointestinal: perforated viscus, appendicitis, inflammatory bowel disease (IBD), infectious colitis, diverticulitis, acute cholecystitis, peptic ulcer perforation, pancreatitis, bowel obstruction
• Urologic: nephrolithiasis, interstitial cystitis
• Spontaneous bacterial peritonitis
• Postoperative: abscess, sepsis, bowel obstruction, injury to internal organs
• Miscellaneous: abdominal trauma, penetrating wounds, infections secondary to intraperitoneal dialysis
• Gynecologic: ruptured ectopic pregnancy, pelvic inflammatory disease (PID), ruptured hemorrhagic ovarian cyst, ovarian torsion, degenerating leiomyoma
• Gastrointestinal: perforated viscus, appendicitis, inflammatory bowel disease (IBD), infectious colitis, diverticulitis, acute cholecystitis, peptic ulcer perforation, pancreatitis, bowel obstruction