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KembaraXtra-Psychology - aspirin
Aspirin (acetylsalicylic acid) is a white crystalline compound originally linked historically to willow bark (Salix alba), identified and first synthesized in 1898 by the German chemist Felix Hoffmann (1868–1946) at Bayer (I. G. Farben). Used widely as an analgesic, it consists of an acetyl group attached to a salicylic acid group, and its strong anti-inflammatory and fever-reducing effects come from inhibiting prostaglandin synthesis by acetylating a site in the prostaglandin-producing enzyme (prostaglandin H₂ synthase/PGHS), blocking the channel through which arachidonic acid from the endoplasmic reticulum is converted into prostaglandins. It also inhibits PGHS forms that help protect the stomach lining. Overdose signs can include gastrointestinal bleeding, dizziness, sweating, thirst, tinnitus, visual disturbances, confusion, drowsiness, breathlessness, nausea, vomiting, coma, and death. Its formula is CH₃COOC₆H₄COOH, and it is associated with ototoxic effects; the name originates from Bayer’s proprietary naming.
Aspirin (acetylsalicylic acid) is a white crystalline compound originally linked historically to willow bark (Salix alba), identified and first synthesized in 1898 by the German chemist Felix Hoffmann (1868–1946) at Bayer (I. G. Farben). Used widely as an analgesic, it consists of an acetyl group attached to a salicylic acid group, and its strong anti-inflammatory and fever-reducing effects come from inhibiting prostaglandin synthesis by acetylating a site in the prostaglandin-producing enzyme (prostaglandin H₂ synthase/PGHS), blocking the channel through which arachidonic acid from the endoplasmic reticulum is converted into prostaglandins. It also inhibits PGHS forms that help protect the stomach lining. Overdose signs can include gastrointestinal bleeding, dizziness, sweating, thirst, tinnitus, visual disturbances, confusion, drowsiness, breathlessness, nausea, vomiting, coma, and death. Its formula is CH₃COOC₆H₄COOH, and it is associated with ototoxic effects; the name originates from Bayer’s proprietary naming.
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