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Symptoms and Signs – Differential Diagnosis of Bacterial Pneumonia
• Viral pneumonias
• Tuberculosis
• Sarcoidosis
• Pulmonary embolism or infarction
• Pulmonary edema
• Parasitic pneumonias
• Lung neoplasm
• Hypersensitivity pneumonitis
• Fungal pneumonias
• Exacerbation of chronic bronchitis
• Drug-induced lung injury
• Bronchiolitis
• Atypical pneumonia
• Viral pneumonias
• Tuberculosis
• Sarcoidosis
• Pulmonary embolism or infarction
• Pulmonary edema
• Parasitic pneumonias
• Lung neoplasm
• Hypersensitivity pneumonitis
• Fungal pneumonias
• Exacerbation of chronic bronchitis
• Drug-induced lung injury
• Bronchiolitis
• Atypical pneumonia
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Symptoms and Signs – Differential Diagnosis of Pleural Effusions, Malignant Disease Associated
• Lung cancer (30% to 40%)
• Breast cancer (20% to 25%)
• Lymphoma (10% to 15%)
• Leukemia (5% to 10%)
• GI tract (5%)
• GU tract (5%)
• Reproductive (3%)
• Lung cancer (30% to 40%)
• Breast cancer (20% to 25%)
• Lymphoma (10% to 15%)
• Leukemia (5% to 10%)
• GI tract (5%)
• GU tract (5%)
• Reproductive (3%)
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Symptoms and Signs – Differential Diagnosis of Pleural Effusions
EXUDATIVE
• Neoplasm: bronchogenic carcinoma, breast carcinoma, mesothelioma, lymphoma, ovarian carcinoma, multiple myeloma, leukemia, Meigs’ syndrome
• Infections: viral pneumonia, bacterial pneumonia, Mycoplasma, TB, fungal and parasitic diseases, extension from subphrenic abscess
• Trauma
• Collagen-vascular diseases: systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), scleroderma, polyarteritis, Wegener’s granulomatosis
• Pulmonary infarction
• Pancreatitis
• Postcardiotomy/Dressler’s syndrome
• Drug-induced lupus erythematosus (hydralazine, procainamide)
• Post abdominal surgery
• Ruptured esophagus
• Chronic effusion secondary to congestive failure
TRANSUDATIVE
• Congestive heart failure (CHF)
• Hepatic cirrhosis
• Nephrotic syndrome
• Hypoproteinemia from any cause
• Meigs’ syndrome
EXUDATIVE
• Neoplasm: bronchogenic carcinoma, breast carcinoma, mesothelioma, lymphoma, ovarian carcinoma, multiple myeloma, leukemia, Meigs’ syndrome
• Infections: viral pneumonia, bacterial pneumonia, Mycoplasma, TB, fungal and parasitic diseases, extension from subphrenic abscess
• Trauma
• Collagen-vascular diseases: systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), scleroderma, polyarteritis, Wegener’s granulomatosis
• Pulmonary infarction
• Pancreatitis
• Postcardiotomy/Dressler’s syndrome
• Drug-induced lupus erythematosus (hydralazine, procainamide)
• Post abdominal surgery
• Ruptured esophagus
• Chronic effusion secondary to congestive failure
TRANSUDATIVE
• Congestive heart failure (CHF)
• Hepatic cirrhosis
• Nephrotic syndrome
• Hypoproteinemia from any cause
• Meigs’ syndrome
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Symptoms and Signs – Differential Diagnosis of Plantar Fasciitis
• Tumor, infection
• Tarsal tunnel syndrome
• Stress fracture
• Other regional tendinitis
• Tumor, infection
• Tarsal tunnel syndrome
• Stress fracture
• Other regional tendinitis
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Symptoms and Signs – Differential Diagnosis of Placenta Previa
• Vasa previa
• Vaginal or cervical trauma
• Placenta percreta
• Placenta increta
• Placenta accreta
• Local malignant neoplasm
• Labor
• Abruptio placentae
• Vasa previa
• Vaginal or cervical trauma
• Placenta percreta
• Placenta increta
• Placenta accreta
• Local malignant neoplasm
• Labor
• Abruptio placentae
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Symptoms and Signs – Differential Diagnosis of Pityriasis Rosea
• Viral exanthem
• Tinea versicolor (the lesions are more brown and the borders are not as ovoid)
• Tinea corporis (can be ruled out by potassium hydroxide examination)
• Secondary syphilis (absence of herald patch, positive serologic test result for syphilis)
• Psoriasis
• Nummular eczema
• Lichen planus
• Eczema
• Drug eruption
• Viral exanthem
• Tinea versicolor (the lesions are more brown and the borders are not as ovoid)
• Tinea corporis (can be ruled out by potassium hydroxide examination)
• Secondary syphilis (absence of herald patch, positive serologic test result for syphilis)
• Psoriasis
• Nummular eczema
• Lichen planus
• Eczema
• Drug eruption
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Symptoms and Signs – Differential Diagnosis of Pityriasis Alba
• Vitiligo
• Tinea
• Psoriasis
• Eczema
• Chemical leukoderma
• Vitiligo
• Tinea
• Psoriasis
• Eczema
• Chemical leukoderma
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Symptoms and Signs – Differential Diagnosis of Pituitary Adenoma
PROLACTINOMA
• Pregnancy
• Postpartum puerperium
• Primary hypothyroidism
• Breast disease
• Breast stimulation
• Drug ingestion (especially phenothiazines, antidepressants, haloperidol, methyldopa, reserpine, opiates, amphetamines, and cimetidine)
• Chronic renal failure
• Liver disease
• Polycystic ovary disease
• Chest wall disorders
• Spinal cord lesions
• Previous cranial irradiation
ACROMEGALY
• Ectopic production of GH-releasing hormone from a carcinoid or other neuroendocrine tumor
CUSHING’S DISEASE
• Diseases that cause ectopic sources of ACTH overproduction (including small cell carcinoma of the lung, bronchial carcinoid, intestinal carcinoid, pancreatic islet cell tumor, medullary thyroid carcinoma, and pheochromocytoma)
• Adrenal adenomas, adrenal carcinoma
• Nelson’s syndrome
THYROTROPIN-SECRETING PITUITARY ADENOMAS
• Primary hypothyroidism
NONSECRETORY PITUITARY ADENOMA
• Non-neoplastic mass lesions of various etiologies (e.g., infectious, granulomatous)
PROLACTINOMA
• Pregnancy
• Postpartum puerperium
• Primary hypothyroidism
• Breast disease
• Breast stimulation
• Drug ingestion (especially phenothiazines, antidepressants, haloperidol, methyldopa, reserpine, opiates, amphetamines, and cimetidine)
• Chronic renal failure
• Liver disease
• Polycystic ovary disease
• Chest wall disorders
• Spinal cord lesions
• Previous cranial irradiation
ACROMEGALY
• Ectopic production of GH-releasing hormone from a carcinoid or other neuroendocrine tumor
CUSHING’S DISEASE
• Diseases that cause ectopic sources of ACTH overproduction (including small cell carcinoma of the lung, bronchial carcinoid, intestinal carcinoid, pancreatic islet cell tumor, medullary thyroid carcinoma, and pheochromocytoma)
• Adrenal adenomas, adrenal carcinoma
• Nelson’s syndrome
THYROTROPIN-SECRETING PITUITARY ADENOMAS
• Primary hypothyroidism
NONSECRETORY PITUITARY ADENOMA
• Non-neoplastic mass lesions of various etiologies (e.g., infectious, granulomatous)
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Symptoms and Signs – Differential Diagnosis of Pinworms
• Perineal yeast/fungal infections
• Perianal itching related to poor hygiene
• Hemorrhoidal disease and anal fissures
• Perineal yeast/fungal infections
• Perianal itching related to poor hygiene
• Hemorrhoidal disease and anal fissures
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Symptoms and Signs – Differential Diagnosis of Pilonidal Disease
• Perianal abscess arising from the posterior midline crypt
• Osteomyelitis
• Hidradenitis suppurativa
• Furuncle
• Coccygeal sinus
• Carbuncle
• Anal fistula
• Perianal abscess arising from the posterior midline crypt
• Osteomyelitis
• Hidradenitis suppurativa
• Furuncle
• Coccygeal sinus
• Carbuncle
• Anal fistula