Published on
​Symptoms and Signs – Differential Diagnosis of Phobias
• Panic attacks: anxiety symptoms seen in specific phobia may resemble panic attacks, but the stimulus in specific phobias or social phobias is clear, whereas panic attacks seem more random.
• Generalized anxiety disorder: difficult to distinguish from social phobia; but in social phobia, the cognitive focus is fear of embarrassment or humiliation, whereas in generalized anxiety disorder, the focus is more internal on the subjective sensations of discomfort.
Picture
Published on
​Symptoms and Signs – Differential Diagnosis of Photosensitivity
• Systemic lupus erythematosus (SLE)
• Solar urticaria
• Porphyria cutanea tarda
• Polymorphous light eruption
• Phototoxic reaction
• Photoallergic reaction
• Drug induced (e.g., tetracyclines)
Picture
Published on
​Symptoms and Signs – Differential Diagnosis of Pituitary Adenoma
PROLACTINOMA
• Pregnancy
• Postpartum puerperium
• Primary hypothyroidism
• Breast disease
• Breast stimulation
• Drug ingestion (especially phenothiazines, antidepressants, haloperidol, methyldopa, reserpine, opiates, amphetamines, and cimetidine)
• Chronic renal failure
• Liver disease
• Polycystic ovary disease
• Chest wall disorders
• Spinal cord lesions
• Previous cranial irradiation
ACROMEGALY
• Ectopic production of GH-releasing hormone from a carcinoid or other neuroendocrine tumor
CUSHING’S DISEASE
• Diseases that cause ectopic sources of ACTH overproduction (including small cell carcinoma of the lung, bronchial carcinoid, intestinal carcinoid, pancreatic islet cell tumor, medullary thyroid carcinoma, and pheochromocytoma)
• Adrenal adenomas, adrenal carcinoma
• Nelson’s syndrome
THYROTROPIN-SECRETING PITUITARY ADENOMAS
• Primary hypothyroidism
NONSECRETORY PITUITARY ADENOMA
• Non-neoplastic mass lesions of various etiologies (e.g., infectious, granulomatous)
Picture
Published on
​Symptoms and Signs – Differential Diagnosis of Pityriasis Rosea
• Viral exanthem
• Tinea versicolor (the lesions are more brown and the borders are not as ovoid)
• Tinea corporis (can be ruled out by potassium hydroxide examination)
• Secondary syphilis (absence of herald patch, positive serologic test result for syphilis)
• Psoriasis
• Nummular eczema
• Lichen planus
• Eczema
• Drug eruption
Picture