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Symptoms and Signs – Differential Diagnosis of Lynch Syndrome
• Familial adenomatous polyposis
• Gardner’s syndrome
• Juvenile polyposis
• Nonhereditary colorectal cancer
• Peutz-Jeghers syndrome
• Familial adenomatous polyposis
• Gardner’s syndrome
• Juvenile polyposis
• Nonhereditary colorectal cancer
• Peutz-Jeghers syndrome
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Symptoms and Signs – Differential Diagnosis of Macrocytosis
• Alcohol abuse
• Folic acid deficiency
• Hypothyroidism
• Liver disease
• Marrow aplasia
• Myelofibrosis
• Reticulocytosis
• Vitamin B12 deficiency
• Alcohol abuse
• Folic acid deficiency
• Hypothyroidism
• Liver disease
• Marrow aplasia
• Myelofibrosis
• Reticulocytosis
• Vitamin B12 deficiency
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Symptoms and Signs – Differential Diagnosis of Inherited Macrothrombocytopenia
• Bernard-Soulier syndrome
• Epstein syndrome
• Fechtner syndrome
• GATA1 mutations
• Gray platelet syndrome
• May-Hegglin anomaly
• Mediterranean macrothrombocytopenia
• Mediterranean stomatocytosis/macrothrombocytopenia
• Montreal platelet syndrome
• MYH9-related disorders
• Paris-Trousseau syndrome
• Platelet-type von Willebrand disease
• Sebastian syndrome
• Sialyl Lewis S antigen deficiency
• Bernard-Soulier syndrome
• Epstein syndrome
• Fechtner syndrome
• GATA1 mutations
• Gray platelet syndrome
• May-Hegglin anomaly
• Mediterranean macrothrombocytopenia
• Mediterranean stomatocytosis/macrothrombocytopenia
• Montreal platelet syndrome
• MYH9-related disorders
• Paris-Trousseau syndrome
• Platelet-type von Willebrand disease
• Sebastian syndrome
• Sialyl Lewis S antigen deficiency
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Symptoms and Signs – Differential Diagnosis of Macular Degeneration
• Diabetic retinopathy
• Histoplasmosis
• Hypertension
• Trauma
• Diabetic retinopathy
• Histoplasmosis
• Hypertension
• Trauma
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Symptoms and Signs – Differential Diagnosis of Malabsorption
Causes of malabsorption:
• Abetalipoproteinemia (autosomal recessive)
• AIDS (Mycobacterium avium-intracellulare, AIDS enteropathy)
• Amyloidosis
• Celiac disease
• Chronic mesenteric ischemia
• Chronic pancreatitis
• Collagenous sprue
• Crohn’s disease
• Eosinophilic gastroenteritis
• Immunoproliferative small intestinal disease (alpha heavy chaindisease)
• Intestinal lymphangiectasia
• Intestinal lymphoma
• Irradiation enteritis
• Lactase deficiency
• Nongranulomatous ulcerative jejunoileitis
• Post gastrectomy
• Small bowel resection
• Small intestinal bacterial overgrowth
• Systemic mastocytosis
• Tropical sprue
• Whipple’s disease
• Zollinger-Ellison syndrome
Causes of malabsorption:
• Abetalipoproteinemia (autosomal recessive)
• AIDS (Mycobacterium avium-intracellulare, AIDS enteropathy)
• Amyloidosis
• Celiac disease
• Chronic mesenteric ischemia
• Chronic pancreatitis
• Collagenous sprue
• Crohn’s disease
• Eosinophilic gastroenteritis
• Immunoproliferative small intestinal disease (alpha heavy chaindisease)
• Intestinal lymphangiectasia
• Intestinal lymphoma
• Irradiation enteritis
• Lactase deficiency
• Nongranulomatous ulcerative jejunoileitis
• Post gastrectomy
• Small bowel resection
• Small intestinal bacterial overgrowth
• Systemic mastocytosis
• Tropical sprue
• Whipple’s disease
• Zollinger-Ellison syndrome
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Symptoms and Signs – Differential Diagnosis of Malaria
• Brucellosis
• Dengue fever
• Influenza
• Leishmaniasis
• Leptospirosis
• Rickettsial diseases
• Trypanosomiasis
• Typhoid fever
• Urinary tract infection (UTI)
• Viral hepatitis
• Yellow fever
• Brucellosis
• Dengue fever
• Influenza
• Leishmaniasis
• Leptospirosis
• Rickettsial diseases
• Trypanosomiasis
• Typhoid fever
• Urinary tract infection (UTI)
• Viral hepatitis
• Yellow fever
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Symptoms and Signs – Differential Diagnosis of Malignant Hyperthermia
• Adverse reaction to monoamine oxidase inhibitor or anticholinergic drug
• Central nervous system infection or space-occupying lesion
• Fever
• Heat stroke
• MDMA (ecstasy), cocaine, alcohol withdrawal, or amphetamine use
• Neuroleptic malignant syndrome
• Pheochromocytoma
• Serotonin syndrome
• Strychnine poisoning
• Thyrotoxicosis
• Adverse reaction to monoamine oxidase inhibitor or anticholinergic drug
• Central nervous system infection or space-occupying lesion
• Fever
• Heat stroke
• MDMA (ecstasy), cocaine, alcohol withdrawal, or amphetamine use
• Neuroleptic malignant syndrome
• Pheochromocytoma
• Serotonin syndrome
• Strychnine poisoning
• Thyrotoxicosis
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Symptoms and Signs – Differential Diagnosis of Lymphedema
• Reflex sympathetic dystrophy
• Obstruction from abdominal or pelvic malignant neoplasm
• Myxedema
• Hypoalbuminemia
• Exclude other causes of edema (e.g., cirrhosis, nephrosis, congestive heart failure)
• Chronic venous stasis
• Reflex sympathetic dystrophy
• Obstruction from abdominal or pelvic malignant neoplasm
• Myxedema
• Hypoalbuminemia
• Exclude other causes of edema (e.g., cirrhosis, nephrosis, congestive heart failure)
• Chronic venous stasis
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Symptoms and Signs – Differential Diagnosis of Lymphangitis
• Group A streptococci
• Mycobacterium kansasii
• Mycobacterium marinum (swimming pool granuloma)
• Nocardia brasiliensis
• Pasteurella multocida
• Sporothrix schenckii (sporotrichosis)
• Staphylococcus aureus
• Wuchereria bancrofti
• Group A streptococci
• Mycobacterium kansasii
• Mycobacterium marinum (swimming pool granuloma)
• Nocardia brasiliensis
• Pasteurella multocida
• Sporothrix schenckii (sporotrichosis)
• Staphylococcus aureus
• Wuchereria bancrofti
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Symptoms and Signs – Differential Diagnosis of Leukocytoclastic Vasculitis
• Benign pigmented purpura
• Cherry angiomas
• Infective endocarditis
• Insect bites
• Rocky Mountain spotted fever
• Septic vasculitis
• Thrombocytopenia (ITP, TTP)
• Wegener’s granulomatosis
• Benign pigmented purpura
• Cherry angiomas
• Infective endocarditis
• Insect bites
• Rocky Mountain spotted fever
• Septic vasculitis
• Thrombocytopenia (ITP, TTP)
• Wegener’s granulomatosis