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​Symptoms and Signs – Differential Diagnosis of Oral Vesicles and Ulcers
• Vincent’s stomatitis
• Systemic lupus erythematosus (SLE)
• Syphilis
• Reiter’s syndrome
• Primary herpes simplex infection
• Pemphigus
• Pemphigoid
• Fungi (histoplasmosis)
• Erythema multiforme
• Crohn’s disease
• Coxsackievirus A (herpangina)
• Behçet’s syndrome
• Aphthous stomatitis
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​Symptoms and Signs – Differential Diagnosis of Neutropenia
• Agranulocytosis
• Aplastic anemias
• Drugs (antibiotics, antithyroidals)
• Immunosuppressive drugs
• Lymphocytic and monocytic leukemias
• Radiation therapy to bone marrow
• Viral infections
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​Symptoms and Signs – Differential Diagnosis of Neutrophilia
PRIMARY (NO OTHER EVIDENT ASSOCIATED DISEASE)
• Hereditary neutrophilia
• Chronic idiopathic neutrophilia
• Chronic myelogenous leukemia (CML) and other
myeloproliferative diseases
• Familial myeloproliferative disease
• Congenital anomalies and leukemoid reaction
• Leukocyte adhesion factor deficiency (LAD)
• Familial cold urticaria and leukocytosis
SECONDARY
• Infection
• Stress neutrophilia
• Chronic inflammation
• Drug induced
• Nonhematologic malignant neoplasm
• Generalized marrow stimulation as in hemolysis
• Asplenia and hyposplenism
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​Symptoms and Signs – Differential Diagnosis of Nipple Lesions
• Accessory nipple
• Cellulitis
• Contact dermatitis
• Neurofibroma
• Nevoid hyperkeratosis
• Paget’s disease
• Papillary adenoma
• Sebaceous hyperplasia
• Trauma
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​Symptoms and Signs – Differential Diagnosis of Nocardiosis
• Actinomycosis
• Aspergillosis
• Cellulitis
• Coccidioidomycosis
• Histoplasmosis
• Kaposi’s sarcoma
• Lung abscess
• Lung tumor
• Mycosis
• Other causes of pneumonia
• Tuberculosis
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​Symptoms and Signs – Differential Diagnosis of Painful Nodules
• Angiolipoma
• Arthropod bite or sting
• Blue rubber bleb nevus
• Dermatofibroma
• Erythema nodosum
• Glomus tumor
• Leiomyoma
• Neuroma
• Osler’s node
• Sweet’s syndrome
• Vasculitis
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