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​Symptoms and Signs – Differential Diagnosis of Non alcoholic Fatty Liver
• Alcohol-induced liver disease (A daily alcohol intake of 20 g in women and 30 g in men [three 12-oz beers or 12 oz of wine] may be enough to cause alcohol-induced liver disease.)
• Autoimmune hepatitis
• Toxin- or drug-induced liver disease
• Viral hepatitis
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​Symptoms and Signs – Differential Diagnosis of Nystagmus
• CNS infections
• Congenital
• Labyrinthine or vestibular lesions
• Medications (e.g., meperidine, barbiturates, phenytoin phenothiazines)
• Multiple sclerosis
• Neoplasm (cerebellar, brainstem, cerebral)
• Optic atrophy
• Other: Arnold-Chiari malformation, syringobulbia, chorioretinitis,
meningeal cysts
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​Symptoms and Signs – Differential Diagnosis of Obesity
• Chronic corticosteroid use
• Cirrhosis
• Congestive heart failure (CHF)
• Cushing’s syndrome
• Hypothalamic disorders
• Hypothyroidism
• Insulinoma
• Nephrotic syndrome
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​Symptoms and Signs – Differential Diagnosis of Obsessive-Compulsive Disorder (OCD)
• Delusions or psychosis, which may be mistaken for obsessive thoughts; distinguished from OCD in that the individual recognizes the ideas are not real
• Major depression, hypochondriasis, and several anxiety disorders with predominant obsessions or compulsions; however, in these disorders, the thoughts are not anxiety provoking or extremes of normal concern
• Other conditions in which compulsive behaviors are seen (e.g., trichotillomania)
• Other psychiatric disorders in which obsessive thoughts occur (e.g., body dysmorphic disorder or phobias)
• Paraphilias or pathologic gambling; distinguished from compulsions in that they are usually enjoyable
• Tics and stereotypic movements that appear compulsive but are not driven by the desire to neutralize an obsession
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​Symptoms and Signs – Differential Diagnosis of Odynophagia
Causes of odynophagia:
INFECTIONS
• Herpes simplex virus
• Cytomegalovirus
• Candidiasis
CHEMICAL, INFLAMMATORY
• Gastroesophageal reflux
• Drug induced (Slow-K, tetracyclines, quinidine)
• Irradiation
• Graft-versus-host disease
• Crohn’s disease
• Dermatologic diseases (pemphigus and pemphigoid)
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​Symptoms and Signs – Differential Diagnosis of Ophthalmoplegia
BILATERAL
• Botulism
• Myasthenia gravis
• Wernicke’s encephalopathy
• Acute cranial polyneuropathy
• Brainstem stroke
UNILATERAL
• Carotid, posterior (third cranial nerve, pupil involved,
communicating aneurysm)
• Diabetic, idiopathic (third or sixth cranial nerve, pupil spared)
• Myasthenia gravis
• Brainstem stroke
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