​Dermatology - Anagen effluvium.

​Dermatology - Anagen effluvium.
Anagen effluvium refers to the widespread and diffuse hair loss that occurs as a result of chemotherapy treatment with alkylating drugs, toxicity, or protein deficiency. The onset is typically swift and widespread following any damage to the hair follicle that hampers its ability to undergo cell division and metabolic processes. The severity of a condition typically increases with the dosage.

The skin remains unaltered. The hair loss is characterized by a widespread and comprehensive pattern, with the hair breaking off at the scalp level. Additionally, the eyebrows, eyelashes, face, and body hair may experience an impact, and the nails exhibit transverse bands or ridges, known as Beau lines.

The diagnosis is made through a clinical assessment, which takes into account the location of the fracture and the patient's medical history. The differential diagnosis encompasses alopecia, telogen effluvium, tinea capitis, and trichotillomania.

There are no viable preventative strategies as long as the hazardous substances remain present. Hair regenerates if chemotherapy or other harmful substances are stopped, or when there is sufficient protein consumption. The regrowth of hair after radiation treatment is influenced by factors such as the kind, depth, and dosage fractionation of the radiation. In certain cases, this regrowth may lead to permanent harm to the stem cells in the hair follicles.