Dermatology - Generalized Fixed Drug Eruption

Dermatology - Generalized Fixed Drug Eruption 
An adverse skin response to a drug that you've eaten or drank is called a fixed drug eruption (FDE). It looks like a single (or sometimes multiple) red patch or plaque.
If the patient is given the same drug again, the rash will happen again at the same spot on the skin within hours of the first use.
Lesions can be itchy, painful, or burning, but most of the time they don't cause any symptoms. In people who have already been exposed, lesions appear 30 minutes to 8 hours after taking the drug.
Lesions stay there if the drug is kept up, and they go away in a few days to a few weeks after the drug is stopped.
Within hours of taking the drug, a clearly defined macule that is round or oval in shape appears. At first there is redness, then patches that range from dark red to violet.
Most of the time, lesions are single, but they can grow and get pretty big. But there may be more than one, and they may be spread out randomly. Lumps can change into a bulla and then an erosion. Especially on the groin area or the inside of the mouth, eroded sores are very painful. The spot is dark brown with violet-colored post-inflammatory hyperpigmentation after it has healed.
It usually affects the skin around the genital area, but it can also happen anywhere, like the perioral and periorbital areas, the conjunctivae, and the oropharynx.

The diagnosis is based on symptoms, and the list of possible causes includes herpes simplex virus infections, Stevens Johnson syndrome, toxic epidermal necrolysis, and erythema multiforme.Stop using the harmful drug and apply strong glucocorticoids to wounds that aren't eroding. For erosions, use an antibiotic ointment. Oral prednisone at a dose of 1 mg/kg body weight for two weeks should be given for broad, generalized, and very painful mucosal lesions.