Dermatology - Gonorrhea
Gonorrhea is a sexually transmitted infection caused by the bacterium Neisseria gonorrhoeae. The predominant manifestation in males is the presence of purulent discharge from the urethra. The majority of men (90%) have symptoms of urethritis within a period of 5 days. The majority of infected women do not show any symptoms, and the most prevalent type of infection occurs in the cervix. Abnormalities Disseminated gonococcal infection manifests as hemorrhagic, painful pustules with erythematous bases on the palm and finger of the hand. The lesions manifest on the extremities and are limited in quantity. The diagnosis is established through clinical examination and verified by laboratory findings and culture. The differential diagnosis comprises urethritis, trichomonas infection, Reiter's syndrome, and cervicitis. To treat localized uncomplicated gonorrhea, administer a single dose of either intramuscular ceftriaxone 125 mg, oral cefixime 400 mg, intramuscular ceftizoxime 500 mg, intramuscular cefotaxime 500 mg, or intramuscular cefoxitin 2 g together with oral probenecid 1 g. For those with a penicillin allergy, administer 2 mg of spectinomycin intramuscularly. To treat disseminated gonococcal infection, provide ceftriaxone 1 g intramuscularly or intravenously every 24 hours, cefotaxime or ceftizoxime 1 g intravenously every 8 hours, or spectinomycin 2 g intramuscularly every 12 hours.
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