Dermatology - Hypopigmentation
Hypopigmentation refers to a condition characterized by a decrease in the natural pigmentation of the skin. Postinflammatory hypomelanosis is invariably associated with melanin depletion. Hypopigmentation frequently occurs with atopic dermatitis, psoriasis, guttate parapsoriasis, and pityriasis lichenoides chronica. Pityriasis versicolor exhibits a distinctive characteristic wherein the hypopigmentation can persist for several weeks even after the active infection has resolved. Hypopigmentation can also occur in cutaneous lupus erythematosus, alopecia mucinosa, mycosis fungoides, lichen striatus, seborrheic dermatitis, and leprosy. Hypopigmentation can also occur as a result of dermabrasion, chemical peels, and intralesional injections of glucocorticoids. The macular patches of depigmentation are indicative of a previous eruption or damage in that area. Finely detailed patterns are frequently observed. The diagnosis is made based on clinical examination, and the possible conditions to consider are pityriasis versicolor, sarcoidosis, scleroderma, lupus, mycosis fungoides, treponematosis, onchocerciasis, leishmaniasis, leprosy, and drug responses. Oral photochemotherapy may be effective in treating postinflammatory hypomelanosis, depending on the specific illness it is connected with. The hypopigmentation caused by glucocorticoid injection and the hypopigmentation resulting from pityriasis alba both cure naturally without any treatment.
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