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MEDICINE 

Dermatology - Molluscum Contagiosum

1/30/2024

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Dermatology - Molluscum Contagiosum 
A self-limiting viral infection of the epidermis, molluscum contagiosum heals on its own—with the exception of immunocompromised people. Males are more likely than females to contract molluscum infections, and they are more common in children and sexually active adults.
Any location, particularly those that are naturally blocked like the axillae, antecubital, popliteal fossae, and anogenital folds, might become infected. Lesions are propagated by autoinoculation. Mollusca may be found in large quantities in atopic dermatitis areas. Adults with STIs may experience symptoms in the lower belly, thighs, groins, and genitalia. One-sided conjunctivitis can result from mollusca in the conjunctiva.
Damage
Confluent mosaic plaques can form from skin-colored, round, oval, hemispherical, single or multiple, distributed discrete papules, nodules, or tumors with a central umbilication or depression. Larger lesions may have a central keratotic block, which can be gently extruded to give the lesion a center dimple or umbilication. An inflammatory halo surrounds the mollusk, signaling the start of spontaneous regression, as a result of the host immune system's reaction to the viral antigen. Significant postinflammatory hyperpigmentation in individuals with dark skin tones may arise following therapy or as a result of spontaneous regression.

Clinical diagnosis is made. Human papillomavirus (HPV), condylomata acuminatum, syringoma, keratoacanthoma, squamous cell carcinoma, basal cell carcinoma, and epidermal inclusion cysts are among the conditions included in the differential.

Mollusca self-resolve, hence no treatment is necessary. Office-based treatments include curettage, cryosurgery, and electrodessication if desired for cosmetic impact. Imiquimod 5% cream might work as well.
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