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​Differential Diagnosis of Amaurosis Fugax
• Retinal migraine: In contrast to amaurosis, the onset of visual loss develops more slowly, usually during a period of 15 to 20 minutes.
• Transient visual obscurations (TVOs) occur in the setting of papilledema; intermittent rises in intracranial pressure briefly compromise optic disc perfusion and cause transient visual loss lasting 1 to 2 seconds, and the episodes may be binocular.
• If the visual loss persists at the time of evaluation (i.e., vision has not yet recovered), the differential diagnosis should be broadened
to include:
• Anterior ischemic optic neuropathy—arteritic (classically giant
cell arteritis [GCA]) or nonarteritic
• Central retinal vein occlusion
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