​Infectious Diseases and Microbiology - Human Metapneumovirus Bronchiolitis (HMPV) ( Human Metapneumovirus )

​Infectious Diseases and Microbiology - Human Metapneumovirus Bronchiolitis (HMPV) ( Human Metapneumovirus ) 

As a member of the paramyxovirus family, HMPV causes pneumonia and bronchiolitis in neonates.
 HMPV, which was identified in 2001, exhibits a global distribution. Although the mode of transmission remains uncertain, it is likely through respiratory droplets. Similar to RSV and influenza, HMPV infections exhibit a seasonal pattern characterized by recurrent epidemics in the winter.

The clinical manifestations of HMPV infection in neonates and children resemble those of RSV disease, which includes pneumonia, bronchiolitis, dyspnea, rhinorrhea, and wheezing.
Infections caused by HMPV are typically milder than those caused by RSV. Otitis media is a condition that is linked to HMPV infections in minors. Individuals who are immunocompromised or elderly are also susceptible to developing mild to severe HMPV infections. Mild respiratory tract infections may be caused by HMPV in the general population.

 HMPV targets the respiratory tract and infects respiratory epithelial cells. Although not fully comprehended, the pathogenesis of HMPV infection is believed to be similar to that of RSV infection.

 Aseptic clinical specimens are subjected to PCR analysis in order to diagnose HMPV infections.
Diagnosis Treatment and HMPV infection lacks a specific treatment or vaccine.