Infectious Diseases and Microbiology - Infant Diarrhea ( Enteropathogenic (EPEC) and Enteroaggregative (EAEC) Escherichia Coli
Enteropathogenic (EPEC) and enteroaggregative (EAEC) Escherichia coli are the bacteria that cause diarrhea in infants. The rods are Gram-negative in nature. EPEC and EAEC are linked to diarrhea in infants, particularly in economies that are still in the process of developing. A diarrhea that is watery and frequently followed by vomiting. EPEC attachment to enterocytes of the small intestine causes a host cell actin rearrangement, which leads to the creation of a pedestal, the loss of microvilli, and a reduction in fluid absorption. This process is referred to as attachment and effacement pathogenesis. EAEC is characterized by the presence of adhesion factors, which lead to the formation of large aggregates and a mucous biofilm. This biofilm prevents the absorption of enterocytes from the small intestine, resulting in diarrhea that is prolonged and watery. In order to avoid being dehydrated, it is essential to restore lost fluids. Elimination of
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