Infectious Diseases and Microbiology - Opportunistic Pneumonia ( Aeruginosa pseudomonas)

​Infectious Diseases and Microbiology - Opportunistic Pneumonia ( Aeruginosa pseudomonas) 
Opportunistic Pneumonia caused by Aeruginosa pseudomonas
Aeruginosa pseudomonas
Motile gram-negative rod. a mandatory aerobe that proliferates easily on a variety of culture media
 This common organism is present in food, plants, water, and soil. It frequently contaminates a wide range of hospital objects and is resistant to several disinfectants.
 

Opportunistic pseudomonas infections can present as urinary tract infections linked to indwelling catheters, recurrent pneumonia in people with cystic fibrosis, and wound infections in burn patients.

Endotoxin, exotoxin A, exoenzyme S, adhesins, and an antiphagocytic capsule are examples of virulence factors. Conditions that facilitate colonization are significant, eg, increased mucus production in lungs of cystic fibrosis patients that limits ciliary clearance, and burns that eliminate skin barriers. Patients with cystic fibrosis have an excess of alginate in their lungs, which produces the matrix needed for living in a biofilm. Exotoxin A is an A-B toxin that functions similarly to diphtheria toxin in that it inhibits protein synthesis and causes cell death. ADP-ribosylating toxin exoenzyme S targets several proteins within the cell.


Pseudomonas has a fruity scent when cultured on standard lab media. It also generates a variety of pigments:
Identification Pyoverdin, a yellow-green chemical that is fluorescent under UV light and can be used to monitor burn victims for infection, is similar to pyocyanin, which gives pus its blue hue.

Due to P aeruginosa's resistance to numerous antibiotics, sensitivity testing is essential. Prevention entails using techniques for infection control that are comparable to those used against other nosocomial viruses.