​Infectious Diseases and Microbiology - Pharyngoconjunctival Fever ( Adenovirus)

​Infectious Diseases and Microbiology - Pharyngoconjunctival Fever ( Adenovirus) 
Adenoviruses, particularly types 3 and 7, are the cause of pharyngoconjunctival fever, which is more common in youngsters. There are roughly 50 distinct adenovirus serotypes identified. Adenoviruses can enter the body through the respiratory system, the fecal-oral pathway, or direct fingerstick inoculation of the eyes.

Fever, pharyngitis, conjunctivitis, and cervical adenopathy are the hallmarks of pharyngoconjunctival fever (adenovirus types 3 and 7).
In addition, adenoviruses cause pharyngitis, pneumonias, and colds in people.
• Acute respiratory illness (ARD), mainly in military recruits, caused by adenovirus types 4 and 7.
• Keratoconjunctivitis (mostly in adults) caused by adenovirus types 8, 19, and 37.
• Acute gastroenteritis in newborns and early children (caused by adenovirus types 40 and 41).
• Adenovirus type 11 hemorrhagic cystitis.
• Adenovirus type 14 pneumonia or severe respiratory disease in people of all ages.

Adenoviruses produce direct cytotoxic harm when they infect intestine and respiratory tract epithelial cells. Cell-mediated immunity eliminates infection; type-specific antibodies offer sustained protection.

Adenovirus infections can be found via PCR, serology, direct antigen detection in clinical specimens, isolation and identification in cell culture, and other methods.
Adenovirus infection does not currently have a specific antiviral medication or vaccination available. The prevention of viral infections can be achieved through handwashing.