![]() Infectious Diseases and Microbiology - Pinworm Infection ( Enterobius vermicularis) A roundworm known as Enterobius vermicularis inhabits the intestines. The most prevalent nematode infection in the US is pinworm infection, which is caused by E vermicularis. Eggs can be consumed through fecal-oral spread or by eating dust that contains eggs. Fecal-oral autoinfection is a possible pathogen. When larvae grow in the perianal region and subsequently return through the rectum, retroinfection takes place. The main sign is pruritus, which can cause severe itching and subsequent bacterial infections. An abnormal migration of the adult worm from the perineum might result in urethritis, vaginitis, salpingitis, or pelvic peritonitis. After consumption, the small intestine is where eggs hatch, and the larvae move to the colon to undergo adult differentiation. During night, the mature gravid female leaves the colon and migrates outside the anus to lay eggs in the perianal region. A few hours later, the eggs become contagious. By perianal sample with an applicator wrapped in transparent adhesive tape (sticky side out), eggs are collected for diagnosis. Stool samples typically don't contain eggs. Mebendazole or pyrantel pamoate can be used to destroy mature worms. In order to stop reinfection, a second dose is administered during the two-week life cycle. Every family member ought to receive care. Prevention entails timely medical attention and proper personal cleanliness.
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