kembara Xtra
  • Introduction
  • Earth
  • Gemstones
  • Medicine
  • Finance
  • Law
  • Psychology
  • Technology
  • Travel The World
  • Who We Are
  • Get In Touch
  • Introduction
  • Earth
  • Gemstones
  • Medicine
  • Finance
  • Law
  • Psychology
  • Technology
  • Travel The World
  • Who We Are
  • Get In Touch

MEDICINE 

Infectious Diseases and Microbiology - Progressive Multifocal Leukoencephalopathy  (human polyomavirus /JC virus ( JCV))

1/20/2024

0 Comments

 
Infectious Diseases and Microbiology - Progressive Multifocal Leukoencephalopathy  (human polyomavirus /JC virus ( JCV)) 

Progressive Multifocal Leukoencephalopathy (PML)
The JC virus, a human polyomavirus, is the cause of PML. 70% to 80% of adults test positive for JCV, which is a common asymptomatic childhood infection spread via respiratory tract droplets.
In immunocompromised people, such as the elderly with immunodeficiency conditions, patients receiving immunosuppressive medication for organ transplantation or chemotherapy for cancer, and patients with AIDS, JCV produces an opportunistic infection of the brain.
Adults with immunosuppressive disorders are susceptible to PML, a demyelinating brain disease. 

Early symptoms include impairments in speech, eyesight, and mental status. The onset is subtle. Within six months of the start of the clinical course, a coma and death result.

 JCV spreads via viremia and is contracted through the respiratory system, resulting in latent infection in several organs. JCV is triggered in immunocompromised people, travels to the brain, and specifically targets and destroys oligodendrocytes, the primary myelin-producing cells in the central nervous system.

 JCV is found by PCR in PML patients' cerebral spinal fluid. Moreover, JCV can be found in brain biopsy tissues using in situ DNA hybridization or PCR.

There is currently no vaccination or particular therapy for JCV infection.
Prevention Notes: PML is a condition that defines AIDS.
Picture
Picture
0 Comments



Leave a Reply.

    Kembara Xtra 

    Facts about medicine and its subtopic such as anatomy, physiology, biochemistry, pharmacology, medicine, pediatrics, psychiatry, obstetrics and gynecology and surgery. 

    Picture

    Archives

    June 2025
    April 2025
    March 2025
    February 2025
    January 2025
    December 2024
    November 2024
    October 2024
    September 2024
    August 2024
    June 2024
    May 2024
    April 2024
    March 2024
    February 2024
    January 2024
    December 2023
    August 2023
    July 2023
    June 2023

    Categories

    All
    Cancer
    Clinical Procedures
    Dermatology
    Infectious Diseases And Microbiology
    Medical Physiology
    Medical Science
    Medical Terms
    Medicine
    Pathology
    Pharmacology
    Surgery
    Symptoms And Signs

    RSS Feed

Powered by Create your own unique website with customizable templates.