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MEDICINE 

Kembara Xtra - Medicine - Borderline Personality Disorder

6/26/2023

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Kembara Xtra - Medicine - Borderline Personality Disorder 

Introduction
Borderline personality disorder (BPD), a mental condition that manifests no later than adolescence or early adulthood, is characterized by a persistent pattern of impulsivity, unpredictable interpersonal connections, and unstable and reactive moods:  Typical actions and variations: Uncertainty in one's self-perception as well as in one's intentions, ideals, and aspirations
- Suicide: ideas, history of attempts, planning - Self-mutilation: pinching, scratching, cutting
Splitting: idealizing then depreciating others; presenting as powerless or victimized; frequent use of the emergency room and subsequent admissions for psychiatric care; high prevalence of linked mental problems; typical lack of behavioral insight. 

Aspects of Geriatrics

Age generally makes symptoms better. Feelings of anxiety and helplessness may be made worse by illness (both acute and chronic).
Pediatric Considerations Children are rarely diagnosed. General medical problems (GMCs) and axis I disorders are more likely.
pregnant women's issues
Borderline behaviors may intensify as a result of pregnancy's potential to worsen stress or heightened concerns.

Prevalence and incidence of disease 

beginning no later than early adulthood or childhood (may go untreated for years) 
10% of all psychiatric outpatients and between 15% and 25% of patients in inpatient psychiatric settings in the United States have BPD, which has a prevalence of 0.5 to 5.9% of the population.

Pathophysiology
Unknown but largely acknowledged, BPD is caused by a confluence of the following: Hereditary characteristics of temperament 
Environment (such as past sexual and/or physical abuse of children, past neglect of children, current domestic strife, and unsuitable parenting techniques) Inadequate modulation of limbic structures by the prefrontal area Genetics
It is unclear whether this condition is more likely to affect first-degree relatives due to genetic or psychological causes.

Risk factors include physical disease, external social circumstances, and childhood sexual and/or physical abuse and neglect. Another risk factor is disrupted family relationships.

The issue of prevention typically affects several generations. Children, caretakers, and close relationships should spend some time and engage in activities apart from the borderline person in order to potentially safeguard them.

Accompanying Conditions
Additional psychiatric illnesses


Comorbid disorders should be recognized as part of the diagnosis by the thorough evaluation.
Functional limitations
- Adaptive and unadaptive coping mechanisms
Stressors that are psychosocial
- The patient's strengths, requirements, and ambitions
Initial evaluations should concentrate on risk factors: - Set up a treatment agreement with the patient and specify therapy objectives.
- Evaluate self-harm, suicidal ideation, and psychosis.

Giving a history that includes: clinic appointments for issues without biological results; conflicts with medical personnel; idealizing or unexplainable hostility toward the doctor; and a history of having unreasonable expectations of the doctor (such as, "I know you can take care of me." Unlike my previous provider, you're the best. 
Obtain more knowledge about patient behaviors (for example, from relatives or a partner).
A history of impulsivity, affective instability, and interpersonal problems A history of self-harm, maybe including suicidal threats or attempts 



clinical assessment 
A thorough physical examination can greatly reduce the likelihood of organic disease (particularly thyroid disease), and there are frequently no obvious abnormalities other than scars from self-mutilation.

Multiple Diagnoses 
Mood disorders: Specifically, disruptive mood dysregulation disorder, a pediatric diagnosis characterized by severe recurrent temper outbursts that manifest verbally or behaviorally and are grossly out of proportion to the situation, may resemble the acting out and intense emotions seen in BPD. Look for other BPD-specific symptoms to distinguish.
Psychotic disorder - While auditory and visual hallucinations may occur, they usually do so in the midst of stressful situations and aren't accompanied by irrational thinking, weird delusions, a lack of emotion, or other undesirable symptoms.
BPD has more severe emotional dysregulation and less severe impulsivity than ADHD, which is an attention deficit hyperactivity disorder.
● GMC

Addiction to substances (SUD) 

Diagnostic testing and investigations
Think about the age of onset. A borderline pattern of behaviors must have existed since childhood or early adulthood in order to meet BPD criteria.
Official psychological evaluations 
Discard any personality changes brought on by a GMC.
Initial examinations (lab, imaging)
To rule out GMC and SUD, use Thyroid Stimulating Hormone (TSH) and a urine drug test Diagnostic Procedures/Other
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) requires that the patient satisfy at least five of the following requirements:  Make an effort to prevent desertion
 Interpersonal connections that are unstable and identity issues
Impulsive actions:
Impulsive behavior causes self-harm in two different ways.
When under stress, a person may engage in suicidal or self-destructive conduct, have mood swings, feel empty, struggle to manage their anger, or become paranoid or dissociative. 

Management
The preferred course of treatment for BPD is outpatient psychotherapy: - Dialectical behavior therapy (DBT) blends notions of distress tolerance, acceptance, and self-awareness with cognitive behavioral procedures for emotional regulation and reality testing.
Using a dialectical approach, therapists are tough-minded supporters who unconditionally welcome patients while also reassuring them to recognize their severe emotional dysfunction and use superior alternative behaviors.
● Consideration should also be given to cognitive-behavioral therapy (CBT), mentalization, schema-focused therapy, and mindfulness-based therapies as additional empirically validated approaches.

Generally Speaking
BPD patients need a higher level of medical attention and greater "intentionality" from the practitioner.
Pay attention to patient management as opposed to "fixing" behaviors: - To reduce patient concern, make regular follow-up appointments.
Establish proper communication boundaries. Meet with the treatment team to prevent dividing the team by patient and to discuss patient difficulties. Usually, the best results from treatment come from combining psychotherapy and medication use.

Medication – Pharmacotherapy can be utilized to treat comorbid Axis I disorders and BPD symptoms even though no specific drugs have been FDA-approved to treat BPD (2) [A].
- Mood stabilizers, selective serotonin reuptake inhibitors (SSRIs), and monoamine oxidase inhibitors (MAOIs) for the treatment of affective dysregulation - Control of impulsive behavior: SSRIs and mood stabilizers
- Cognitive-perceptual symptoms: short-term antipsychotic use
When prescribing, take into account the high rate of self-harm and suicidal behavior.
SSRIs are playing a less significant role with more emphasis on mood stabilizers and atypical antipsychotics, however research is ambiguous and inconsistent. Anxiolytics are normally contraindicated due to weakened inhibition that may lead to increased impulsivity.


Sources of Referral

A patient may or may not require more frequent visits if there is a higher risk of self-harm or self-defeating behaviors and there are fewer community resources available (e.g., outpatient day programs for suicidal patients; substance abuse programs).


Surgical Techniques

Transcranial stimulation may enhance executive performance, according to recent yet conflicting research.

additional medication
Dietary supplementation with omega-3 fatty acids has demonstrated positive effects for lowering emotional reactivity.

Those behind admission

To adjust medication, administer psychotherapy for crisis intervention, and stabilize patients from psychosocial stressors, hospitalizations should be kept to a minimum and be brief.
For the following reasons, extended inpatient hospitalization should be taken into account: - Severe or persistent suicide thoughts or risk to others
- Co-occurring substance use disorders and/or noncompliance with outpatient or partial hospitalization therapies - Comorbid Axis I diseases that pose a greater risk to the patient's life, such as eating disorders and mood disorders 

Take Action 

 Arrange appointments that are brief, more regular, and targeted to allay patients' concerns about interactions with their doctor or other provider and to lessen the possibility of provider burnout.
Stress the value of making healthy lifestyle changes (such as increasing exercise, rest, and food).
Patient Monitoring Keep an eye out for any signs of self-harm or suicidal thoughts or actions.

Patients' Education 
To help patients understand their disease process and take part in the treatment plan, involve them in the diagnosis process.

Borderline habits may lessen with age and with passage of time.
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