​Pathology - Acute Pancreatitis

​Pathology - Acute Pancreatitis 
Pathophysiology 
The intrapancreatic activation of enzymes is the etiology of this inflammatory disease. Common symptoms include pain, nausea, vomiting, and intestinal ileus (seen here by a lack of bowel noises). Acute pancreatitis is frequently caused by trauma, drug side effects, hypertriglyceridemia, gallstones, and alcohol consumption.
Pancreatic autodigestion is accompanied by bleeding, necrosis, interstitial edema, intra-abdominal fluid accumulation, and the release of vasoactive peptides. The sickness can vary in severity and has the potential to be lethal. Increased AST/ALT and alkaline phosphatase levels, together with elevated serum amylase and lipase, are found in laboratory examination. If gallstone blockage is present, these levels are frequently accompanied by hyperbilirubinemia. Patients are treated with pain management, hydration support, and close observation to prevent complications like necrotizing disease or damage to the surrounding vascular structures.