​Pathology - Anoxic Brain Injury

​Pathology - Anoxic Brain Injury 
Pathophysiology 
A history of prolonged cardiac arrest that resulted in diminished brain perfusion may produce anoxic brain damage. The brain tissue becomes ischemic due to decreased perfusion. Watershed areas, or the regions of the brain between two arterial supplies that lose perfusion and become ischemic earliest after vascular insult, are the most susceptible to anoxic brain injury. The neocortex, basal ganglia, and hippocampal regions are the brain's watershed regions. Unfortunately, there is no cure for this person because neurons have a limited capacity for regeneration.