Pathology - End Stage Dilated Cardiomyopathy

Pathology - End Stage  Dilated Cardiomyopathy
Pathophysiology 
This patient's condition, which is characterized by a damaged myocardium and accompanying cardiac dysfunction, is most frequently caused by ischemic heart disease, which accounts for about 65% of cases. Additional frequent causes of dilated cardiomyopathy include drug-induced (cancer chemotherapy drugs), genetic metabolic problems, neuromuscular diseases, toxins (alcohol) or viral infections. Patients may eventually experience decompensated states of insufficient perfusion, which often involve fluid retention in the abdomen, pulmonary circulation, and peripheral extremities. A constricted pulse pressure is frequently observed, resulting from an inadequate systolic contraction. 

The greatly inflated left ventricle is the cause of the displaced point of maximum impulse (PMI), and the failing heart's interruption of optimum flow is the cause of the audible murmur. Due to chronic heart ischemia, decreased ventricular compliance causes the S3 gallop that has been observed. Every bodily system is impacted, and the goal of medical treatment is to eliminate extra fluid and lessen the strain on the heart. The best course of action in cases where the myocardium is as severely injured as this one is is cardiac transplantation.