Epidemiology of Ankylosing Spondylitis: Prevalent in young males who test positive for HLA-B27. Clinical signs and symptoms include peripheral arthritis of the spine and major joints, uveitis, lower back pain and stiffness (particularly in the morning), elevated ESR, and a bamboo spine on radiographs. Etiology and Epidemiology of Psoriatic Arthritis: Usually appears between the ages of 30 and 50; 15% to 20% of psoriasis patients have this condition. Clinical signs include arthritis of the hands, foot, and major joints; sausage fingers (synovitis of the tendon sheath of the fingers); pitting of fingernails; inflammation of the eyes; and a radiograph-detected "pencil-in-cup" deformity of the DIP joints. The etiology and epidemiology of reactive arthritis: reaction to a previous gastrointestinal or urinary tract infection (e.g., Shigella, Salmonella, or Chlamydia); particularly prevalent in young males who test positive for HLA-B27. Clinical signs and symptoms: The classic trifecta of conjunctivitis or uveitis, arthritis, and nongonococcal urethritis manifests as lower back discomfort and asymmetric joint stiffness, generally in the ankles or knees. Enteropathies Arthritis: Most common in people who are HLA-B27 positive; associated with inflammatory bowel disease or gastrointestinal infections. Clinical signs and symptoms: Erythema nodosum and asymmetric oligoarthritis of the major joints (knees, spine) usually go away within a few months when inflammatory bowel disease is treated.
Treatments NSAIDs, physical therapy, and intra-articular steroid injections are the three main forms of treatment for spondyloarthropathies.
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