Phamacology - Ethosuximide
Anticonvulsant medication having ethosuximide activity that is specifically effective against absence seizures. Types of Blocks for Action Mode For the purpose of counteracting the slow (3Hz), spike and wave, ring pattern that is thought to be significant in absence epilepsy, T-type Ca2+ channels were established in thalamic neurons. Oral admin. By means of the cytochrome P450 system, oxidized. 50 hours is the half life. Use in Clinical Settings Although it is not effective against partial or tonic-clonic seizures, the drug of choice for absence seizures remains effective. Allergies and Reactions The symptoms include pancytopenia, anorexia, and upset stomach. Rash, sleepiness, and weariness are symptoms. Both coma and respiratory depression can be the result of an overdose.
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