Pharmacology - Adenosine

Pharmacology - Adenosine
Adenosine is an anti dysrhythmic agent. 

G-protein-coupled adenosine receptors are those that are activated by the mode of action. The action (on A1 receptors) is caused by the inhibition of Ca2+ channel opening and the enhanced opening of K+ channels (the effect is comparable to the impact that acetylcholine has on cardiac muscarinic receptors). Two of its most important activities are the slowing of AV conduction and the negative chronotropic action it has on the SA node.

In the event that the duration of activity is short. The half-life is ten seconds.

Use in Clinical Settings 
Treatment of paroxysmal supraventricular tachycardia that has been terminated.

Adverse Effects 
As a result of the rapid clearance of adenosine, the adverse effects, which include flushing, chest discomfort, dyspnea, and bronchospasm, are only temporary.