​Pharmacology - Ceftazidime

​Pharmacology - Ceftazidime 
The bactericidal action of ceftazidime is to prevent the production of bacterial cell walls during cell division.

Mode of Action 
 'Building blocks' are peptide chains that attach to the backbone of peptidoglycan cell walls; this enzyme is bound to and inhibited by this molecule.

Administered intravenously (IV) through a deep intramuscular (IM) injection, intravenous (IV) infusion, or catheter. (Probenecid blocks its passage into all bodily fluids; eliminated in urine). approximately one to one and a half hours.

Resistance 
Activated by beta-lactamases produced by bacteria.

Use in Clinical Settings 
Gram-positive & Gram-negative bacterial and Pseudomonas aeruginosa infections.

Potential Side Effects 
Anaphylaxis, gastrointestinal problems, pseudomembranous colitis, fever, arthralgia, rashes, and urticaria are all examples of hypersensitivity reactions.