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Pharmacology - Chloramphenicol
Bacterial protein synthesis is inhibited by chloramphenicol.
Action Process
The process of transpeptidation is blocked.Administered orally or intravenously, it enters the cerebrospinal fluid and central nervous system, is broken down in the liver, and then eliminated in urine.
Clinical Application
Primarily prescribed for severe cases of typhoid, penicillin-resistant meningitis, and other potentially fatal H. influenzae infections. Apply directly to the eye to treat bacterial infections.
Potential Side Effects
Depression of the bone marrow connected to dose. Circulatory collapse, aggression, and vomiting are symptoms of the "Grey baby" syndrome in newborns that do not have the necessary inactivating enzyme. In certain people who are genetically predisposed, aplastic anemia can develop.
Bacterial protein synthesis is inhibited by chloramphenicol.
Action Process
The process of transpeptidation is blocked.Administered orally or intravenously, it enters the cerebrospinal fluid and central nervous system, is broken down in the liver, and then eliminated in urine.
Clinical Application
Primarily prescribed for severe cases of typhoid, penicillin-resistant meningitis, and other potentially fatal H. influenzae infections. Apply directly to the eye to treat bacterial infections.
Potential Side Effects
Depression of the bone marrow connected to dose. Circulatory collapse, aggression, and vomiting are symptoms of the "Grey baby" syndrome in newborns that do not have the necessary inactivating enzyme. In certain people who are genetically predisposed, aplastic anemia can develop.
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