​Pharmacology - Erythromycin

​Pharmacology - Erythromycin 
Clindamycin works by preventing bacteria from making new proteins.

Action Process
 Blocks the transfer RNA's (and the peptide's) movement from the A site to the P site. Dispensed by mouth, intramuscular injection, or intravenous infusion. About 2.5 hours is the half-life. Disseminated extensively; enters abscesses; does not reach brain or cerebrospinal fluid. Found mostly in bone. The active metabolite is produced in the liver and then eliminated in the urine.

Clinical Application 
Streptococci, staphylococci, and numerous anaerobes (with the exception of Clostridium difficile) are all effectively treated. For infections of the lungs, bones, joints, skin, and soft tissues, as well as abscesses in the lungs.

Risks of irregular bowel movements, skin rashes, yellowing of the skin, pseudomembranous colitis.