​Pharmacology - Heparin

​Pharmacology - Heparin 
Heparin 
Taking action 
This prevents the blood from coagulating.

Mode of Action 
In addition to having an effect on IXa, XIa, and XIIa, it has the ability to speed up the action of antithrombin III (ATIII), which in turn increases its inactivation of factors IIa (thrombin) and Xa.

injected intravenously or administered subcutaneously. The elimination half-life is between forty and ninety minutes; renal excretion.Activated partial thromboplastin time is taken into consideration while determining the appropriate dosage. Protamine sulfate treated an overdose of the substance.


Use in Clinical Settings 
Deep vein thrombosis, pulmonary embolism, unstable angina, and acute peripheral artery occlusion are all treatment options for this condition.

Adverse Effects
Blood loss is the primary adverse impact. The symptoms include thrombocytopenia, hypersensitivity responses, and osteoporosis.