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Pharmacology - Hydralazine
The actions of hydralazine include relaxing the artery smooth muscle, which in turn lowers blood pressure.
The mechanism of action involves interfering with the release of calcium ions from the sarcoplasmic reticulum in smooth muscle cells of the vascular apparatus.
Orally administered. About one to three hours is the half-life.
Use in clinical settings
Extremely high blood pressure, especially while an individual is pregnant.
Adverse Effects
Symptoms such as palpitations, hypotension, gastrointestinal (GI) problems, disorientation, and allergic responses (which can become severe with prolonged use)
The actions of hydralazine include relaxing the artery smooth muscle, which in turn lowers blood pressure.
The mechanism of action involves interfering with the release of calcium ions from the sarcoplasmic reticulum in smooth muscle cells of the vascular apparatus.
Orally administered. About one to three hours is the half-life.
Use in clinical settings
Extremely high blood pressure, especially while an individual is pregnant.
Adverse Effects
Symptoms such as palpitations, hypotension, gastrointestinal (GI) problems, disorientation, and allergic responses (which can become severe with prolonged use)
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