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Pharmacology - hydroxocobalamin
Restores the blood picture in megaloblastic anemias, such as pernicious anemia, and leads to a partial to complete recovery of the neurological condition, which is characterized by subacute combined degeneration of the spinal cord.
Method of Action
It is important for the conversion of methyl-tetrahydrofolate (methyl-FH4) to tetrahydrofolate (FH4), which is essential for the synthesis of thymidylate and, consequently, for the synthesis of DNA.
By intramuscular injection (IM).
Use in Clinical Settings
to treat pernicious anemia as well as other conditions that are caused by a lack of vitamin B12.
Adverse Reactions
Hypokalemia at the beginning of treatment, as well as symptoms such as nausea, dizziness, headache, and hypersensitivity reactions.
Restores the blood picture in megaloblastic anemias, such as pernicious anemia, and leads to a partial to complete recovery of the neurological condition, which is characterized by subacute combined degeneration of the spinal cord.
Method of Action
It is important for the conversion of methyl-tetrahydrofolate (methyl-FH4) to tetrahydrofolate (FH4), which is essential for the synthesis of thymidylate and, consequently, for the synthesis of DNA.
By intramuscular injection (IM).
Use in Clinical Settings
to treat pernicious anemia as well as other conditions that are caused by a lack of vitamin B12.
Adverse Reactions
Hypokalemia at the beginning of treatment, as well as symptoms such as nausea, dizziness, headache, and hypersensitivity reactions.
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