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Pharmacology - Ketamine
An Action of Ketamine
Dissociative anesthesia is a type of anesthesia in which the patient may stay conscious but receives effective pain relief and forgetfulness for a brief period of time. Analgesia administered at doses below those of a subanesthetic.
The mode of action involves blocking the ion channel of the NMDA type glutamate receptor.
I.v. or as an administrator. I.V. administration results in a rapid beginning of activity and a brief duration of action. Decomposed in the liver; half life is two and a half hours.
Use in Clinical Settings
The administration of anesthesia and its maintenance for operations that are either diagnostic or surgical in nature. Children, who are less likely to experience adverse psychotic side effects, are the primary target population for small procedures.
Effects That Are Bad
Because of the stimulation of the sympathetic system, the heart rate and blood pressure are both increased. Movement of the muscles that is not voluntary. In the course of recovery, hallucinations, delerium, and dysphoria may occur. Depression of the respiratory system in overdose.
An Action of Ketamine
Dissociative anesthesia is a type of anesthesia in which the patient may stay conscious but receives effective pain relief and forgetfulness for a brief period of time. Analgesia administered at doses below those of a subanesthetic.
The mode of action involves blocking the ion channel of the NMDA type glutamate receptor.
I.v. or as an administrator. I.V. administration results in a rapid beginning of activity and a brief duration of action. Decomposed in the liver; half life is two and a half hours.
Use in Clinical Settings
The administration of anesthesia and its maintenance for operations that are either diagnostic or surgical in nature. Children, who are less likely to experience adverse psychotic side effects, are the primary target population for small procedures.
Effects That Are Bad
Because of the stimulation of the sympathetic system, the heart rate and blood pressure are both increased. Movement of the muscles that is not voluntary. In the course of recovery, hallucinations, delerium, and dysphoria may occur. Depression of the respiratory system in overdose.
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