​Pharmacology - Levothyroxine

​Pharmacology - Levothyroxine 
An increase in the metabolism of carbohydrates, proteins, and lipids; an increase in the pace at which the body functions at rest.

Method of Operation 
When the medication penetrates cells, it undergoes a conversion to T3, which then travels to the nucleus and binds to a membrane receptor for the thyroid hormone. The complex is responsible for activating transcription, which in turn leads to the production of messenger RNA (mRNA) as well as the fabrication of proteins and enzymes that are accountable for the metabolic actions of T4.

Orally administered. Enjoys a lengthy half-life.Given that certain meals can impede absorption, it is best to administer the medication on an empty stomach.
Use in Clinical Settings
Hypothyroidism is a condition. When treating myxoedema coma, liothyronine is employed.

Adverse Effects
Symptoms include a loss of weight, palpitations, sleeplessness, heat intolerance, and nervousness.