​Pharmacology- Losartan

​Pharmacology-  Losartan 
Action 
Vasoconstrictor tone is decreased, which results in a reduction in blood pressure.

The mode of action involves inhibiting the action of angiotensin II on the receptor that is associated with angiotensin II (AT1 subtype).

Orally administered. The half-life of the metabolite is between three and four hours.

Use in clinical settings 
This includes hypertension, congestive heart failure, and nephropathy.

Adverse effects 
There is hypotension and dizziness. A hyperkalemic state may develop.
It does not result in the dry cough or angioedema that is usually seen with ACE inhibitors.