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Pharmacology- Losartan
Action
Vasoconstrictor tone is decreased, which results in a reduction in blood pressure.
The mode of action involves inhibiting the action of angiotensin II on the receptor that is associated with angiotensin II (AT1 subtype).
Orally administered. The half-life of the metabolite is between three and four hours.
Use in clinical settings
This includes hypertension, congestive heart failure, and nephropathy.
Adverse effects
There is hypotension and dizziness. A hyperkalemic state may develop.
It does not result in the dry cough or angioedema that is usually seen with ACE inhibitors.
Action
Vasoconstrictor tone is decreased, which results in a reduction in blood pressure.
The mode of action involves inhibiting the action of angiotensin II on the receptor that is associated with angiotensin II (AT1 subtype).
Orally administered. The half-life of the metabolite is between three and four hours.
Use in clinical settings
This includes hypertension, congestive heart failure, and nephropathy.
Adverse effects
There is hypotension and dizziness. A hyperkalemic state may develop.
It does not result in the dry cough or angioedema that is usually seen with ACE inhibitors.
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