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Pharmacology - Minoxidil
Reduces blood pressure and causes vascular dilatation that is noticeable and long-lasting.
The mechanism of action involves activating K+ channels, which in turn hyperpolarizes the membrane, and activates actin, which inhibits voltage-dependent Ca++ channels, hence lowering the contraction of K+ channels.
Orally administered. About four hours is the half-life.
Use in clinical settings
Hypotension of the most severe kind.Additionally used as a topical treatment for baldness.
Adverse Reaction
As a result of salt and water retention, tachycardia, and angina, the medication is administered in conjunction with a loop diuretic and a beta blocker. Hirsutism .
Reduces blood pressure and causes vascular dilatation that is noticeable and long-lasting.
The mechanism of action involves activating K+ channels, which in turn hyperpolarizes the membrane, and activates actin, which inhibits voltage-dependent Ca++ channels, hence lowering the contraction of K+ channels.
Orally administered. About four hours is the half-life.
Use in clinical settings
Hypotension of the most severe kind.Additionally used as a topical treatment for baldness.
Adverse Reaction
As a result of salt and water retention, tachycardia, and angina, the medication is administered in conjunction with a loop diuretic and a beta blocker. Hirsutism .
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