Pharmacology - Prazosin

Pharmacology - Prazosin
An Action of Prazosin 
Vasodilation, which resulted in a decrease in blood pressure
A reflex beta 1-receptor response to the decreased blood pressure causes an increase in the heart rate.
decreased tone of the bladder sphincter

Prostate capsule and bladder neck smooth muscle hypertrophy inhibition is the goal of this treatment.

Mode of Action 
blocking the activity of endogenous and exogenous agonists on 1-receptors is the goal of this study. A tamsulosin is an antagonist that acts on the alpha-1A receptor.

The process of absorbing, distributing, and eliminating 
It is taken orally, has a plasma half-life of three to four hours, and is metabolized by the liver, with substantial first-pass metabolism.
Administered orally, tamsulosin has a plasma half-life of 10–15 hours and is metabolized by the liver. The half-life of doxazosin is 22 hours.

Use in Clinical Settings 
Prazosin and doxazosin are medications that are prescribed for severe hypertension.
Tamsulosin, prazosin, and doxazosin are also treatments that are utilized for benign prostatic hypertrophy.

Adverse Effects 
Orthostatic hypotension, dizziness, hypersensitivity reactions, sleeplessness, and occasionally priapism are some of the side effects of prazosin. It is also possible for tamsulosin to produce back pain and irregular ejaculatory patterns.